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Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10205-3

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By 2012, ONT had unveiled its first sequencing data, and Nanopore sequencing quickly established itself as a quick method for generating long reads without DNA synthesis, albeit with a higher error rate than some earlier methods. (Nanopore reads had an accuracy of about 85-90 percent per base in 2017, compared to over 99 percent for Illumina. Recent improvements, though, have boosted this accuracy to more than 99 percent for most applications.)